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Description

Giorgi C, Danese A, Missiroli S, Patergnani S, Pinton P

Prepare a dilution series with 7 points

Increased notch activity in T2D induces expression of SREBP1 in liver through constitutive activation of mTORC1, promoting fat deposition, and increases expression of G6Pase and PEPCK in liver in a FOXO1-dependent manner, promoting glucogenesis, and ultimately exacerbating IR